Which option accurately describes the impact the Columbian Exchange had on the indigenous people of the Americas?

Question

The Columbian Exchange enabled the trade of the coca plant, which was later made into an early form of cocaine.
The Columbian Exchange was a barter system between European explorers and the indigenous people, who exchanged gold for rum and spices.
Europeans brought rum and coffee to the Americas in exchange for bananas and papaya.
Europeans brought disease in the form of germs that infected the indigenous people of the Caribbean.

B?

Answer 1

Wait, I meant D sorry

Answer 2

Yes, D.