The answer would depend on the specific areas shown on the map of Canada, as different regions may be affected differently by each of these factors. However, generally speaking:
- Acid rain (A) can have severe effects on forests, lakes, and wildlife, particularly in areas with sensitive ecosystems.
- Overfishing (B) primarily affects marine environments and fish populations, especially in coastal regions.
- Urbanization (C) can lead to habitat loss, pollution, and increased resource consumption, impacting both terrestrial and aquatic ecosystems.
- Clear-cutting (D) is very damaging to forest ecosystems, leading to habitat destruction, soil erosion, and biodiversity loss.
- Wetland destruction (E) can severely impact water quality, flood control, and wildlife habitats.
If the areas in question are heavily forested, clear-cutting (D) would likely have the most damaging effects due to its direct and immediate impact on forest ecosystems. In contrast, if the areas are coastal or involve freshwater ecosystems, wetland destruction (E) could be more impactful.
For a definitive answer, more context regarding the specific areas on the map is needed.