Which of these was the largest and most constant issue facing the United States during the era of "Manifest Destiny?"

Question

Responses

A whether labor unions would be allowed to formwhether labor unions would be allowed to form

B whether states would allow women the right to votewhether states would allow women the right to vote

C whether Indians would be relocated to North Carolinawhether Indians would be relocated to North Carolina

D whether slavery would spread across the United States

Answer 1

The largest and most constant issue facing the United States during the era of "Manifest Destiny" was:

D) whether slavery would spread across the United States.

During this period in the mid-19th century, the expansion of the United States westward raised significant questions about the extension of slavery into new territories and states, leading to intense political conflict and contributing to the sectional tensions that eventually culminated in the Civil War.