The most accurate comparison of the results of the Columbian Exchange from your options is:
Both Europeans and Native Americans benefited from the trade, but the harm done to the Native Americans was greater.
The Columbian Exchange involved the transfer of crops, animals, and ideas between the Old World (Europe) and the New World (Americas). While Europeans gained access to new crops and resources that significantly improved their diets and economies, Native Americans suffered immensely from the introduction of diseases, loss of land, and violent conflicts, resulting in a population decline and significant cultural changes.