The description that best explains Mendel's law of segregation is:
The two alleles for each gene separate as homologous chromosomes move apart during anaphase I.
Mendel's law of segregation states that during the formation of gametes, the two alleles for each gene segregate (separate) from each other, ensuring that each gamete carries only one allele for each gene. This process occurs during anaphase I of meiosis, when homologous chromosomes are pulled apart, resulting in the separation of the alleles they carry.