All of the responses provided reflect tensions and clashes between early European settlers and Native Americans. However, if you are looking for the most specific causes that led to conflicts, here are a few points to consider:
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Europeans wanted the Native Americans to convert to European religions. - This often led to clashes as Europeans sought to impose their beliefs on Indigenous populations.
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Native Americans believed the Europeans were hiding gold and silver from them. - This suspicion often led to distrust and conflict, particularly as Europeans were indeed often in pursuit of wealth.
While all four points can be seen as contributing factors to the clashes, the desire for conversion and issues surrounding wealth tend to be highlighted as key areas of conflict.