which of the strands (lagging or leading) requires primase to act more frequently?

Question

a. the leading strand
b. the lagging strand

Answer 1

b. the lagging strand

The lagging strand requires primase to synthesize RNA primers more frequently because it is synthesized in short segments called Okazaki fragments, which necessitate the addition of a new primer for each fragment. In contrast, the leading strand is synthesized continuously and requires only a single RNA primer at the beginning of the replication process.