The direct effects of Pizarro’s and Cortés’s defeat of Native Americans include:
- Settlement and colonization of Florida under Spanish rule
- Settlement and colonization in the Southwest under Spanish rule
- Inspiration for other Europeans to begin explorations and settlement
The option "fighting between the Spanish and the French" is more indirect and does not directly stem from the actions of Pizarro and Cortés. The first three options are directly related to the consequences of their conquests.