The true statement among the given options is:
They affect different regions in different ways.
Natural disasters can have varying impacts depending on a region's geography, infrastructure, preparedness, and various social factors. The other statements are not accurate: natural disasters can occur in many places around the world, not just the Ring of Fire; their impacts can indeed be mitigated by laws, infrastructure, and effective communication; and while natural disasters may involve potential events, the definition of natural disasters is more focused on the occurrence and impact rather than just the potential for an event to occur.