The statement "Most enzymes are much larger than the substrates they act on" is true about enzymes. Enzymes are typically large protein molecules, while substrates are usually smaller molecules that enzymes act upon.
To clarify the other statements:
- Enzymes do not exclusively bind to substrates; they can also bind to other molecules, such as inhibitors or activators.
- Enzymes are present in nearly all living organisms, found in various types of cells, not just certain ones.
- Enzymes can change their shape during the reaction process, particularly in the mechanism known as the "induced fit" model, where the enzyme adjusts its shape to better fit the substrate.
Thus, the most accurate option is that most enzymes are much larger than the substrates they act on.
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