The correct statement is:
B: Prokaryotic cells lack membrane-bound organelles, whereas eukaryotic cells have membrane-bound organelles.
To clarify the incorrect statements:
A: Eukaryotic cells are generally larger than prokaryotic cells, not smaller.
C: Both eukaryotic and prokaryotic cells have ribosomes, but they differ in size and structure.
D: Prokaryotic cells do not contain a nucleus; instead, they have a nucleoid region where their genetic material is located. Eukaryotic cells do contain a nucleus.