The statement that best assesses how Congress’s bicameral structure developed during the formation of the U.S. Constitution is:
"At the Constitutional Convention, the Framers sought to satisfy the major issue of state representation and incorporate an intrabranch check to prevent tyranny."
This reflects the compromise between states with large populations and those with smaller populations, leading to the creation of a two-house legislature (the House of Representatives and the Senate). This structure was designed to balance representation while preventing any single entity from gaining too much power.