To determine which ordered pair is a solution to the equation \( 2.5y - 3x = 10 \), we can test each pair by substituting the values into the equation.
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For the pair \((-5, -2)\): \[ 2.5(-2) - 3(-5) = -5 + 15 = 10 \quad (True) \]
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For the pair \((-5, 2)\): \[ 2.5(2) - 3(-5) = 5 + 15 = 20 \quad (False) \]
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For the pair \((5, -2)\): \[ 2.5(-2) - 3(5) = -5 - 15 = -20 \quad (False) \]
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For the pair \((5, 2)\): \[ 2.5(2) - 3(5) = 5 - 15 = -10 \quad (False) \]
The only ordered pair that satisfies the equation is \((-5, -2)\). Thus, the correct answer is: \[ \boxed{(-5, -2)} \]