The Homestead Steel Strike of 1892 was primarily sparked by wage cuts and the management's desire to break the union rather than specifically by layoffs due to lack of profit. The Carnegie Steel Company, led by Henry Clay Frick, announced significant wage cuts for workers at the Homestead plant, which led to a strong backlash from the Amalgamated Association of Iron and Steel Workers (the union representing the workers).
While financial struggles can impact job security, in this case, the immediate cause of the strike was the management's attempt to reduce labor costs and undermine the union's power, rather than layoffs due to the factory's inability to turn a profit. Therefore, the point about wage cuts would be a key factor, rather than layoffs specifically.
If you are looking for a specific answer to which response led to the Homestead Steel Strike from a list, please provide the complete list of responses for more accurate assistance.