Selenium (Se) is located in group 16 of the periodic table, and its chemical properties are most similar to those of other elements in the same group, particularly in terms of their oxidation states and reactivity.
Among the options given:
A. Sodium (Na) - is an alkali metal, in group 1. B. Arsenic (As) - is in group 15, but it is chemically similar to selenium as they are both metalloids and are close in the periodic table. C. Oxygen (O) - is in group 16, but is a non-metal and has different reactivity compared to selenium. D. Bromine (Br) - is in group 17 and is a halogen.
The chemically most similar element to Selenium among the choices provided is B. Arsenic (As), due to being in the same region of the periodic table and exhibiting similar chemical behaviors as a metalloid.