The most accurate description of a contribution of the Gupta Golden Age is: The Gupta made advancements in medicine, such as one of the first smallpox inoculations.
Additionally, the Gupta Empire is known for significant achievements in mathematics, such as the development of the concept of zero and advancements in the decimal system, but they did not invent what Europeans called the Roman numeral system. Roman numerals originated from ancient Rome, not the Gupta Empire.
In literature, while the Gupta Empire produced notable works, it is important to clarify that they did not write the first epic poems in history, as earlier works existed in various cultures.