The correct statement that compares prokaryotic and eukaryotic chromosomes is:
Prokaryotes tend to only have one chromosome while eukaryotes have many.
To clarify the other options:
- Prokaryotic chromosomes are typically smaller than eukaryotic ones, not larger.
- Prokaryotic chromosomes are typically circular, while eukaryotic chromosomes are linear.
- Prokaryotic chromosomes do not form nucleosomes; nucleosomes are associated with eukaryotic DNA packaging.