The correct comparison between prokaryotic and eukaryotic chromosomes is:
Prokaryotes tend to only have one chromosome while eukaryotes have many.
Prokaryotic chromosomes are typically circular and usually exist as a single chromosome, whereas eukaryotic chromosomes are linear and there are multiple chromosomes within a eukaryotic cell. Additionally, eukaryotic DNA is wrapped around histone proteins to form nucleosomes, while prokaryotic DNA is not organized into nucleosomes in the same way.
So, the correct statement among the provided choices is the last one.