The best explanation of the effects of the Yamasee War on the restructuring of settlements and shift in power in South Carolina is:
Indigenous power declined, while colonial power increased.
The Yamasee War (1715-1717) resulted in significant losses for the Indigenous tribes involved, leading to a decline in their power and influence in the region. In contrast, the colonial authorities and British settlers were able to strengthen their control and expand their settlements in South Carolina post-war.