Which of the following BEST describes how the Spanish and Hernando DeSoto impacted the Native Americans living in the southeastern region of North America?

Question

A.
Native Americans benefitted from learning about new technologies from the Europeans.
B.
They formed a strong alliance and became trading partners.
C.
The Native Americans were introduced to new foods.
D.
Thousands of Native Americans died as a result of diseases spread by contact with European

Answer 1

The BEST option that describes the impact of the Spanish and Hernando DeSoto on the Native Americans living in the southeastern region of North America is:

D. Thousands of Native Americans died as a result of diseases spread by contact with Europeans.

This option highlights the devastating consequences of European contact, as diseases brought by the Spanish decimated Native American populations who had no immunity to them.