A. Filtration and evaporation
Filtration is a method that separates mixtures based on particle size, allowing smaller particles to pass through while larger particles are retained. Evaporation can also separate components of a mixture based on boiling points, but it's not primarily about particle size. Therefore, the best answer focusing on particle size is that filtration is the main method used, but in the context of your options, none of them categorize as strictly size-separation methods beyond filtration.
If you strictly focus on particle size separation, the better answer among the given options is C. Filtration and chromatography, where chromatography can also involve separation based on particle size or other properties in some contexts.
However, filtration is definitely the primary method of particle size separation.