The best statement of the Law of Conservation of Energy from the options provided is:
The amount of energy put out by a simple machine must equal the amount of energy put into the machine.
This statement aligns with the principle that energy cannot be created or destroyed, only transformed from one form to another. However, it's important to note that in practical applications, some energy is often lost due to inefficiencies (e.g., friction), which is why the output is usually less than the input in real-world machines.