To simplify the expression for the base \( 16 \), we can analyze its factors. The correct factorization that is most useful for simplifying expressions involving powers of \( 16 \) is:
\[ 16 = 2 \cdot 2 \cdot 2 \cdot 2 = 2^4 \]
Among the options provided, the correct response that expresses \( 16 \) in terms of its factors is:
\[ 16 = 2 \cdot 2 \cdot 2 \cdot 2 \]
Thus, the answer is:
16 = 2 ⋅ 2 ⋅ 2 ⋅ 2.