To simplify the expression \((z + 4)(z - 4)\), we can use the difference of squares formula, which states that \((a + b)(a - b) = a^2 - b^2\).
Here, \(a = z\) and \(b = 4\), so we get:
\[ (z + 4)(z - 4) = z^2 - 4^2 = z^2 - 16 \]
Now let's compare this with the options given:
- \(2z^2 - z^2 - 8\) simplifies to \(z^2 - 8\), which is not equivalent.
- \(z^2 + 4z - 4z - 16\) simplifies to \(z^2 - 16\), which is equivalent.
- \(z(z) + 4z(z) - 4(4)\) expands to \(z^2 + 4z^2 - 16\), which simplifies to \(5z^2 - 16\), not equivalent.
- \(z^2 - 8z - 16\) is not equivalent either.
Thus, the expression that is equivalent to \((z + 4)(z - 4)\) is:
\(z^2 - 16\)
So, the correct response from the options is: \(z^2 + 4z - 4z - 16\).