The best summary of how Columbus’s and Vasco da Gama’s motivations were different is:
Both had three motivating factors; however, Columbus achieved spices, God, and glory, whereas da Gama achieved glory and silk.
This response accurately reflects that Columbus was primarily motivated by the pursuit of land and the spread of Christianity as well as the search for spices, while da Gama focused on establishing trade routes for valuable goods like silk and spices, along with glory through his explorations.