When dividing the expression \(4x + 2y - 8\) by \(2b\), you will still have the variables \(x\), \(y\), and \(b\) present in the quotient.
The division can be expressed as:
\[ \frac{4x + 2y - 8}{2b} = \frac{4x}{2b} + \frac{2y}{2b} - \frac{8}{2b} \]
Each term in the resulting expression will still contain at least one variable, so the total number of different variables present in the quotient remains 3: \(x\), \(y\), and \(b\).
Therefore, the correct answer is 3.