To find the ratio of 16 to 4096, you can express it as a fraction:
\[ \text{Ratio} = \frac{16}{4096} \]
To simplify this fraction, divide both the numerator and the denominator by 16:
\[ \frac{16 \div 16}{4096 \div 16} = \frac{1}{256} \]
Thus, the ratio of 16 to 4096 is \(1:256\).