what would be the result of a sytosine base being substituted or a thymine base in a DNA segment during DNA replication?

1 answer

If a cytosine (C) base is substituted for a thymine (T) base during DNA replication, it would result in a mutation known as a C to T transition. This mutation changes the nucleotide sequence in the DNA strand. During subsequent DNA replication cycles, the new complementary strand would pair adenine (A) with the substituted thymine (T) instead of guanine (G) pairing with cytosine (C). This alteration would cause a change in the genetic code, potentially leading to the synthesis of a different protein or disrupting its functionality.