What were the earliest civilizations in Mesopotamia?

Question

What would be a physical description of Mesopotamia?
Cultural description of southwest Asia?( main language, religion, resources,etc)

Answer 1

http://www.thenagain.info/WebChron/MiddleEast/EarlyMesopoCivs.html

http://www.mesopotamia.co.uk/geography/home_set.html

In your third question, are you asking about southwest Asia now or in ancient times?