To determine the type of mutation error causing a specific disorder, we would typically need more context about the genetic changes involved. However, I can provide a brief overview of each mutation type:
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Insertion: This occurs when extra nucleotides are added to the DNA sequence. This can disrupt the reading frame if the number of inserted nucleotides is not a multiple of three.
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Frameshift: This type of mutation happens when nucleotides are added or removed from the DNA sequence, altering the reading frame of the gene. It usually has significant effects on the resulting protein.
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Substitution: This mutation occurs when one nucleotide is replaced by another. It can be silent (no change in the amino acid), missense (changes an amino acid), or nonsense (creates a stop codon).
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Deletion: Involves the loss of nucleotides from a DNA sequence, which can also disrupt the reading frame if the number of deleted nucleotides is not a multiple of three.
If you provide more details about the disorder or the specific mutation that has been identified, I can help pinpoint which type of mutation is responsible.
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