Cells that do not perform mitosis include:
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Mature Neurons: Most mature neurons in the human body are post-mitotic, meaning they do not undergo mitosis and generally do not divide.
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Cardiac Muscle Cells: Cardiac myocytes (heart muscle cells) largely do not replicate by mitosis after they have fully differentiated. While there is some evidence suggesting limited regenerative capacity, they do not typically undergo significant division.
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Skeletal Muscle Cells: Mature skeletal muscle fibers are formed by the fusion of myoblasts and do not undergo mitosis. However, satellite cells (which are a type of stem cell) can divide and contribute to muscle repair.
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Red Blood Cells: Mature red blood cells (erythrocytes) in mammals lack a nucleus and do not perform mitosis. They are produced from precursor cells in the bone marrow through a different process of differentiation.
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Oocytes: Primary oocytes begin meiosis but are arrested in development and do not complete this process until fertilization occurs. As a result, they do not undergo mitosis in the traditional sense after they have entered the meiotic program.
These cells are typically in a differentiated state where they perform specialized functions and do not have the capacity for division like other cell types that actively undergo mitosis.