The correct response is:
Fractional-reserve banks only hold a portion of all deposits made while full-reserved banking hold 100% of every depositor's funds on hand.
This statement accurately captures the fundamental difference between the two banking systems. In fractional-reserve banking, banks keep a fraction of deposits as reserves and use the majority for lending, while in full-reserve banking, banks hold the entire amount of each depositor's funds in reserve, providing greater security for depositors.