what is the main difference between RNA polymerases in eukaryotes and prokaryotes

Answer 1

The main difference between RNA polymerases in eukaryotes and prokaryotes is the number and specificity of the polymerases. Eukaryotes have three different RNA polymerases (RNA pol I, II, and III) that are specialized for different types of RNA synthesis, while prokaryotes have only one RNA polymerase. In addition, eukaryotic RNA polymerases require accessory proteins called transcription factors to bind to specific DNA sequences called promoters, whereas prokaryotic RNA polymerase can bind to promoters directly.