The main difference between prokaryotic and eukaryotic cells is:
B. Prokaryotes lack membrane-bound organelles.
Prokaryotic cells, such as bacteria, do not have membrane-bound organelles like the nucleus, endoplasmic reticulum, or mitochondria that are found in eukaryotic cells (e.g., plant and animal cells). Prokaryotes have a simpler structure and typically smaller size than eukaryotic cells.
To clarify the other options:
- A is incorrect because prokaryotes do have a cell membrane.
- C is incorrect because prokaryotes do have ribosomes to synthesize proteins, though the ribosomes are different in size and structure compared to those in eukaryotes.
- D is incorrect; prokaryotes use DNA as their genetic material, similar to eukaryotes.