The main difference between prokaryotic and eukaryotic cells is:
a. Prokaryotes lack membrane-bound organelles.
Prokaryotic cells do not have membrane-bound organelles, whereas eukaryotic cells do have them (such as the nucleus, mitochondria, and endoplasmic reticulum).
The other options are incorrect because:
- b. Prokaryotes lack a cell membrane on the outside. (This is false; prokaryotes do have a cell membrane.)
- c. Prokaryotes lack ribosomes to make proteins. (This is false; prokaryotes do have ribosomes, although they differ in size and structure from those in eukaryotes.)
- d. Prokaryotes use RNA instead of DNA. (This is false; prokaryotes use DNA as their genetic material, just like eukaryotes.)