The correct response is:
Prokaryotes do not store their genes in a nucleus like eukaryotes do.
This statement highlights a fundamental structural difference between prokaryotic and eukaryotic cells, which significantly affects gene regulation and expression. Prokaryotes have a simpler organization, typically containing a single circular DNA molecule located in the cytoplasm, whereas eukaryotes have multiple linear chromosomes housed within a membrane-bound nucleus. The other statements contain inaccuracies regarding the processes of gene regulation in prokaryotes and eukaryotes.