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Single nucleotide polymorphisms (SNPs) are single base pair substitutions that occur at a specific position on the DNA sequence, while Random Amplified Polymorphic DNA (RAPD) analysis involves amplifying random regions of genomic DNA. Therefore, whether or not a SNP would have an influence on the results of an RAPD analysis would depend on a variety of factors such as the location of the SNP, the size and location of the amplified region, primer specificity, and the number of SNPs present in the sequence. In general, SNPs that occur within or near the amplified region may alter or affect the amplification profile, causing a difference in the RAPD pattern. However, the extent of this influence could be negligible or significant depending on the technical parameters of the analysis.
What influence would a SNP have on the results of an RAPD?
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