What happens during the initiation stage of transcription? RNA polymerase binds to the promoter. RNA polymerase makes more RNA. RNA polymerase reaches the end of the gene.

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During the initiation stage of transcription, RNA polymerase binds to the promoter region of the gene that is to be transcribed. The promoter is a specific DNA sequence located at the start of the gene and is crucial for the regulation of gene expression. Once RNA polymerase is bound to the promoter, it unwinds the DNA double helix, forming a transcription bubble that allows access to the template strand of the DNA.

At this stage, RNA polymerase does not yet make RNA; that process occurs in the next stage, called elongation, where RNA polymerase synthesizes the RNA transcript by adding complementary RNA nucleotides based on the DNA template strand.

So, to summarize: during initiation, RNA polymerase binds to the promoter, prepares for transcription, and then begins the RNA synthesis process. The making of RNA begins after initiation, during the elongation phase.

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The correct answer is: "RNA polymerase binds to the promoter."

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