During cell division, the processes of mitosis and meiosis take place, each serving distinct roles in the life cycle of the organism.
Mitosis is the process by which somatic (body) cells divide. It consists of several stages that follow an initial interphase, where the cell prepares for division by growing and replicating its DNA. Mitosis involves four main phases:
- Prophase: Chromosomes condense and become visible, and the nuclear envelope breaks down.
- Metaphase: The chromosomes align at the cell's equatorial plate.
- Anaphase: The sister chromatids of each chromosome are pulled apart to opposite poles of the cell.
- Telophase: Nuclear membranes start to form around the two sets of separated chromosomes, and the cell prepares to divide.
After these phases, the cell undergoes cytokinesis, leading to the formation of two genetically identical daughter cells, each containing 46 chromosomes (23 pairs from the mother's and father's genetic contributions).
Meiosis, on the other hand, is the specialized process for the formation of germ cells (gametes, such as sperm and eggs) and involves two rounds of cell division, known as meiosis I and meiosis II, after an interphase. This process results in gametes with half the number of chromosomes (23), ensuring that when fertilization occurs, the resulting zygote has the correct diploid number of chromosomes.
In meiosis I, homologous chromosomes (each consisting of two sister chromatids) pair up and may exchange segments in a phenomenon called crossover (or homologous recombination). This occurs during prophase I:
- The chromosomes physically align and can form structures called chiasmata at points of contact.
- Sections of the chromatids may be exchanged between homologous chromosomes, leading to new combinations of genes. This increases genetic diversity among the gametes, contributing to the variation in traits within a population.
After meiosis I, the two homologous chromosomes separate, followed by meiosis II, where the sister chromatids are divided, ultimately producing four non-identical gametes, each with 23 chromosomes. This process of crossover and genetic variation is crucial for evolution and the adaptability of species.