The most relevant piece of evidence supporting the claim that trade changed after the fall of Constantinople is:
Europeans found alternate trade routes to bypass the Muslims.
After the fall of Constantinople in 1453, which marked a significant shift in trade dynamics, European powers sought new trade routes to access Asian goods without going through Ottoman-controlled territories. This led to the Age of Exploration, during which European explorers searched for maritime routes to Asia, ultimately resulting in significant changes in global trade patterns.