The fate of the English Colony of Roanoke is one of history's great mysteries, but we do know that the colony was found deserted in 1590, with no trace of the colonists. Of the options provided, the most accurate choice reflects the historical context:
C. Supplies were delayed due to the battle with the Spanish Armada.
While we cannot say for certain what happened to the colonists, it is known that the return of supplies was delayed because of the conflict with the Spanish Armada in 1588. Other explanations have been considered, but none of the provided options can be definitively stated as the cause of the colonists' disappearance.