The specialized molecules on the surface of the blastocyst that facilitate adhesion to the uterus are known as adhesion molecules. These molecules help the blastocyst adhere to the uterine lining, known as the endometrium, thereby allowing implantation to occur. Two important adhesion molecules involved in this process are:
1. Integrins: Integrins are a class of transmembrane proteins that help mediate cell-cell and cell-extracellular matrix interactions. In the blastocyst, integrins play a crucial role in binding to specific receptors on the surface of uterine epithelial cells.
2. Selectins: Selectins are another class of adhesion molecules, consisting of cell surface proteins that mediate transient interactions between cells. Specifically, L-selectin has been found on the blastocyst and is involved in the initial interactions with the uterine epithelium.
By expressing these adhesion molecules, the blastocyst is able to interact with the appropriate receptors on the uterine lining, leading to attachment and implantation. These molecular interactions are essential for successful pregnancy establishment.
what are specialized molecules on the surface of blastocyst that facilitate adhesion of blastocyst to uterus
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