Based on the provided passage, the Mound Builders primarily lived in regions that extended from the Great Lakes to the Gulf of Mexico and east of the Mississippi River to the Appalachian Mountains.
Here’s a breakdown of the regions as they might relate to those descriptions:
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Region A (if it includes parts of the Great Lakes and eastward towards the Appalachian Mountains)
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Region B (if it includes areas along the Mississippi River southward towards the Gulf of Mexico)
Without the actual map, the best two choices for the regions where the Mound Builders primarily lived would likely be selections that correspond to the areas described in the passage. Please refer to the map provided in your materials to select the two regions that match those locations.