To derive the equation represented by the algebra tiles:
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On the left side, there are 5 rectangles (each representing a variable \(x\)) and 4 squares (each representing the number 1).
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This can be expressed as \(5x + 4\).
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On the right side, there are 6 squares labeled negative 1. This means there are 6 negative units, which can be represented as \(-6\).
Putting these together, we get the equation:
\[ 5x + 4 = -6 \]
Therefore, the correct response is:
5x + 4 = -6 (5 x plus 4 equals negative 6).