To determine the most likely creator of the cartoon you described, we would consider the historical context in which such a cartoon might have been produced. Given that the cartoon features Thomas Jefferson—a key figure in American history and a proponent of democracy—and the symbolism of the eagle (often representing the United States), the cartoon seems to address themes of liberty versus tyranny.
One potential creator who comes to mind is a political cartoonist from the early to mid-19th century, as this was a period when political cartoons became popular in the United States and were used to comment on political issues, including those related to governance and the dangers of despotism.
If we were to narrow it down further, a cartoonist such as Thomas Nast, who worked in the mid- to late-19th century, might fit the bill, although his focus was more on later political issues, including corruption and the battle against despotism in a different context than Jefferson's time.
However, if the cartoon specifically relates to Jefferson's era and the early formation of the United States, a political cartoon published in the late 18th or early 19th century could potentially be attributed to artists like Benjamin Franklin, who created cartoons that advocated for liberty and critiqued tyranny.
Without the actual image or additional context, it's challenging to provide a definitive answer, but foremost, it seems like a politically charged representation created by an artist invested in highlighting the struggles for democracy against authoritarianism, likely during or shortly after Jefferson's time.