A frameshift mutation occurs when bases are deleted or inserted in such a way that it alters the reading frame of the DNA sequence. In this case, you need to find a sequence that results from a deletion of one or more nucleotides.
Let's analyze the provided options:
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ATG AAG TTG GCT AA - This seems to have deleted one base pair (the "T" from "TTT"), which shifts the reading frame.
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ATG TTT GGC TAA - This maintains the same reading frame, as it appears to have deleted "AAG" entirely, but the sequence isn't an exact frame shift.
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ATG UAA GTT TGG CTA A - This option includes "U," which is not a valid base in DNA, ruling it out.
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ATG AAG TTT GGC GCA TAA - This includes an extra "GCA," which results in an insertion, rather than a deletion.
The correct choice that represents a frameshift mutation due to deletion is:
ATG AAG TTG GCT AA.
1 answer