To provide accurate options, I would need the specific phrases or excerpts from President Roosevelt's address that you are considering. However, I can suggest that key phrases revealing a turning away from U.S. isolationism typically refer to concepts of international cooperation, support for allies, a commitment to global stability, or the need to assist countries threatened by aggressors.
If you have the phrases from the address, please share them, and I can help you identify the two that indicate a shift in U.S. foreign policy.