The correct answers to fill in the blanks are:
- Substitution mutations occur when a single base is changed to a different base pair.
- Deletion mutations remove one or more bases from a segment of DNA, resulting in a frameshift mutation.
- Insertion mutations are also considered frameshift mutations, and occur when one or more extra bases are added to a segment of DNA.
So the completed sentence would be:
"There are multiple types of mutations in DNA substitution mutations occur when a single base is changed to a different base pair deletion mutations remove one or more bases from a segment of DNA, resulting in a frameshift mutation insertion mutations are also considered frameshift mutations, and occur when one or more extra bases are added to a segment of DNA."