To find the ratio of sisters to brothers, we first need to determine the number of brothers in the family.
Given that there are a total of 12 siblings and 4 of them are sisters, we can find the number of brothers by subtracting the number of sisters from the total:
\[ \text{Number of brothers} = \text{Total siblings} - \text{Number of sisters} = 12 - 4 = 8 \]
Now we have 4 sisters and 8 brothers. The ratio of sisters to brothers can be expressed as:
\[ \text{Ratio of sisters to brothers} = \frac{\text{Number of sisters}}{\text{Number of brothers}} = \frac{4}{8} \]
To simplify this ratio, we can divide both numerator and denominator by their greatest common divisor, which is 4:
\[ \frac{4 \div 4}{8 \div 4} = \frac{1}{2} \]
Therefore, the ratio of sisters to brothers is:
\[ \boxed{1:2} \]
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