The slope of the line that passes through (2, -4) and (-6, 2) is:

-4/3

3/2

1/4

-3/4

-4/3

slope = y/x
distance of y is -4 to 2 = 6
distance of x is 2 to -6 = -8
(y/x) = -6/8 = -3/4